What happens with person’s consciousness under the influence of the psychoactive drink ayahuasca? How does the brain react to ayahuasca when monitored by a modern research equipment? What role does the traditional environment play in the effect of ayahuasca? Do the indigenous people of amazonian jungle perceive the effects of ayahuasca differently than people from other cultures? Is there a connection among the participants’ brains when experiencing the ritual? Answers to these and to many other questions are searched for by the international scientific project under the leadership of Czech scientists - Neurobiology of Ayahuasca Used in a Traditional Environment.